from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.float16).to('cuda')
pipeline.load_lora_weights('xotopo/anaya1800', weight_name='ioeDCbe7sYXJ6JNU5DHj5_pytorch_lora_weights.safetensors')
image = pipeline('your prompt').images[0]

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers