Composite Retroelement-Age V2 extends the retroelement annotation to CpGs compatible across EPIC v1.0 and v2.0 and was trained by 10-fold-cross-validated elastic net.
Predicts
chronological age
Species
Homo sapiens
Tissue
whole blood
Data type
DNA methylation
Model type
elastic net regression
Year
2024
Use with pyaging
python
1import pyaging as pya
23pya.pred.predict_age(adata,["retroelementagev2"])
Ndhlovu, Lishomwa C., et al. "Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements." Aging Cell 23 (2024): e14288.