Reference-based constrained deconvolution returning the CD4+ T cell proportion from EPIC-array blood methylation. Pyaging uses the paper's automatic 600-CpG top-hypermethylated/top-hypomethylated reference, not the paper's preferred 450-CpG EPIC IDOL library.
1import pyaging as pya
2
3pya.pred.predict_age(adata, ["deconvolutebloodepiccd4tcell"])
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Salas, L.A., Koestler, D.C., Butler, R.A. et al. An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray. Genome Biology 19, 64 (2018).
