Whole-blood DNA-methylation score for cardiovascular risk. The paper's final cross-study learner stacks cohort-specific elastic-net Cox models; the packaged pyaging implementation is a 235-CpG linear score followed by a sigmoid.
1import pyaging as pya
2
3pya.pred.predict_age(adata, ["cvdwesterman"])
Browse every clock in the
pyaging Clock Catalogue.
Westerman, K. et al. Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics. Journal of the American Heart Association 9, e015299 (2020).
