from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('openfree/leonardo-dicaprio', weight_name='leonardo-dicaprio.safetensors')
image = pipeline('Leonardo DiCaprio as professional football player, happy face, black hair, real photo, 26K
').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers