from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('mlgawd/sydneypi', weight_name='my_first_flux_lora_v2.safetensors')
image = pipeline('hot sweeney at the beach').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers