About
PhenoBIC is a deep learning model that predicts marker co-expression phenotype of cells by performing image classification of the biomarker "imprint" (staining pattern) of the cell.
This enables automated and operator-independent cell biomarker expression classification with spatial multiplex imaging data.
Citing
Please cite the following if you use PhenoBIC:
- PhenoBIC paper: Sankaranarayanan, A. et al. PhenoBIC: operator-free single-cell spatial phenotyping in multiplex imaging data using deep learning of cell staining patterns. bioRxiv 2026. https://www.biorxiv.org/content/10.64898/2026.06.11.731702v1
Running PhenoBIC
