from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('longnthgmedia/flux_lora_meme_v2', weight_name='flux_lora_meme_v2.safetensors')
image = pipeline('A surprised or shocked Shiba Inu, sitting at a desk with its paws on a keyboard. Its wide eyes and open mouth convey an expression of intense surprise or panic, as if reacting to something unexpected on the computer screen. The background features a colorful, abstract painting reminiscent of 'The Scream' by Edvard Munch, adding to the overall sense of dramatic tension. The combination of the dog's expression and the artistic backdrop creates a humorous and exaggerated scene, as if the Shiba Inu has just seen something shocking online.').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers