from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('julientassy/fantasy-pixel-lora-v1', weight_name='fantasy_pixel_lora_v1.safetensors')
image = pipeline('fntsy_pixel pixel art portrait of a footballer, dark slate background, 16-color palette').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers