from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('guui/YANN_flux_lora_v1-lora', weight_name='YANN_flux_lora_v1_000001750.safetensors')
image = pipeline('a beautiful landscape').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers