from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('stabilityai/stable-diffusion-xl-base-1.0', torch_dtype=torch.float16).to('cuda')
pipeline.load_lora_weights('brushpenbob/darkglow-3-0', weight_name='DarkGlow_3.0.safetensors')
image = pipeline('Your custom prompt').images[0]

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers