from diffusers import AutoPipelineForText2Image
import torch

device = "cuda" if torch.cuda.is_available() else "cpu"

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to(device)
pipeline.load_lora_weights('Keltezaa/kate-beckinsale-flux', weight_name='Kate_Beckinsale_Flux.safetensors')
image = pipeline(' beautiful detailed photograph, hair cascading over her shoulders, wearing a boatneck dress, standing in a cafe, smile').images[0]

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers