from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('black-forest-labs/FLUX.1-dev', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('Himanshu806/manosouthf', weight_name='manosouthf.safetensors')
image = pipeline('a woman in a green sari standing in front of a building, holding a bag in her hand. The building has a door with a name board on it, and there are plants and flowers in the background manoSouthf').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers