A benchmark for evaluating whether single-cell RNA-seq normalization methods preserve known gene-gene correlation structure. It provides two complementary ground-truth catalogs:
Promoter-reporter catalog — Datasets where a fluorescent reporter (GFP/DsRed) is driven by a known gene's promoter. The reporter and its target gene should be positively correlated.
Allelic exclusion catalog — PBMC and B cell datasets where immunoglobulin light chain allelic… See the full description on the dataset page:
https://huggingface.co/datasets/valsv/scrna-coregulation-benchmark.
