Variant-effect-prediction benchmark of saturation genome editing (SGE) function
scores. SGE edits the endogenous genomic locus (CRISPR-HDR, typically in haploid
HAP1 cells), so every assayed SNV has a direct experimental functional measurement
in genomic coordinates — an axis orthogonal to the clinical/population/statistical
labels of the other evals_* datasets, and one that covers near-exon noncoding
(splice-region, proximal-intronic) SNVs, not just missense.
No… See the full description on the dataset page:
https://huggingface.co/datasets/marin-dna/evals_sge.
