This is a compact, structured snapshot of the spot decision-support chain: continuous CD4
transcriptional-program axes → CRISPRi perturbation targets → GO-BP/Reactome pathways → drugs and
mechanisms → bounded brain-exposure and safety evidence.
The source assay contains four donors and Rest, Stim8hr and Stim48hr conditions. Same-condition and
ordered cross-condition comparisons are included. These are cross-sectional perturbation… See the full description on the dataset page:
https://huggingface.co/datasets/KiritSingh/spot-CD4-program-to-drug.