AssayBench: An Assay-Level Virtual Cell Benchmark
Dataset Summary
AssayBench is a benchmark for evaluating computational models on phenotypic CRISPR screen prediction — a core capability of the "virtual cell" paradigm. It contains 1,901 curated CRISPR screen entries derived from 1,565 unique screens in BioGRID ORCS (version 2025), spanning five major classes of cellular phenotypes. Given a textual description of a CRISPR screen experiment, the task is to predict a ranked… See the full description on the dataset page: https://huggingface.co/datasets/Genentech/assaybench.