Cortex-specific DNA-methylation chronological-age estimator trained by elastic net on 1,047 post-mortem cortical samples; its 347-CpG weighted score is back-transformed to years.
Predicts
chronological age
Species
Homo sapiens
Tissue
brain cortex
Data type
DNA methylation
Model type
elastic net regression
Year
2020
Use with pyaging
python
1import pyaging as pya
23pya.pred.predict_age(adata,["corticalclock"])
Shireby, G. L., et al. "Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex." Brain 143.12 (2020): 3763-3775.
