Pan-tissue, pan-histone chronological-age predictor trained on gene-level ChIP-seq enrichment from seven histone modifications; ElasticNet feature selection is followed by truncated-SVD PCA and automatic relevance determination regression.
1import pyaging as pya
2
3pya.pred.predict_age(adata, ["camillopanhistone"])
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de Lima Camillo, L. P., Asif, M. H., Horvath, S., Larschan, E., & Singh, R. Histone mark age of human tissues and cell types. Science Advances 11, eadk9373 (2025).