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popV/
tabula_muris_All

Name: tabula_muris_All
Availability: InStock

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Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. Despite rapid advances over recent years, many of the molecular and cellular processes that underlie the progressive loss of healthy physiology are poorly understood. To gain a better insight into these processes, here we generate a single-cell transcriptomic atlas across the lifespan of Mus musculus that includes data from 23 tissues and organs. We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence, genomic instability and changes in the immune system. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides molecular information about how the most important hallmarks of ageing are reflected in a broad range of tissues and cell types.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	scanvi	svm	xgboost	Consensus Prediction
B cell	3685	0.86	0.90	0.85	0.89	0.89	0.76	0.79	0.91
mesenchymal stem cell	1657	0.86	0.88	0.92	0.75	0.79	0.90	0.87	0.94
basal cell of epidermis	1507	0.84	0.87	0.83	0.88	0.83	0.86	0.81	0.90
granulocyte	1605	0.83	0.86	0.79	0.85	0.80	0.74	0.84	0.89
endothelial cell	1485	0.87	0.93	0.84	0.78	0.78	0.88	0.85	0.93
microglial cell	1338	0.99	0.99	0.95	0.99	0.98	0.99	0.99	1.00
T cell	1266	0.78	0.82	0.67	0.70	0.62	0.66	0.74	0.84
keratinocyte	1253	0.83	0.88	0.82	0.88	0.87	0.88	0.86	0.90
macrophage	967	0.49	0.67	0.60	0.59	0.27	0.51	0.55	0.71
classical monocyte	825	0.80	0.64	0.60	0.51	0.56	0.76	0.81	0.86
granulocytopoietic cell	834	0.65	0.82	0.65	0.75	0.63	0.66	0.77	0.83
bladder urothelial cell	642	0.98	0.98	0.97	0.97	0.94	0.99	0.97	0.99
mesenchymal stem cell of adipose tissue	664	0.80	0.84	0.77	0.66	0.67	0.92	0.81	0.89
fibroblast of cardiac tissue	644	0.95	0.95	0.85	0.61	0.67	0.95	0.91	0.96
endothelial cell of coronary artery	564	0.81	0.88	0.64	0.57	0.58	0.88	0.81	0.91
skeletal muscle satellite cell	469	0.98	0.97	0.96	0.97	0.96	0.97	0.96	0.98
proerythroblast	449	0.56	0.56	0.49	0.55	0.27	0.50	0.66	0.61
kidney proximal convoluted tubule epithelial cell	438	0.82	0.86	0.35	0.80	0.87	0.87	0.87	0.88
bronchial smooth muscle cell	428	0.95	0.96	0.84	0.90	0.91	0.96	0.93	0.96
myeloid cell	422	0.56	0.66	0.45	0.55	0.42	0.72	0.68	0.75
hepatocyte	371	0.98	1.00	0.98	0.99	0.99	0.99	0.99	0.99
type B pancreatic cell	410	0.96	0.97	0.97	0.96	0.97	0.98	0.97	0.98
bladder cell	391	0.98	0.96	0.97	0.73	0.86	0.98	0.95	0.99
promonocyte	415	0.63	0.74	0.70	0.63	0.71	0.78	0.82	0.85
DN4 thymocyte	385	0.42	0.51	0.37	0.38	0.10	0.54	0.63	0.58
basal cell	350	0.97	0.97	0.97	0.97	0.96	0.97	0.96	0.98
monocyte	395	0.63	0.60	0.52	0.46	0.53	0.73	0.78	0.81
enterocyte of epithelium of large intestine	373	0.92	0.93	0.87	0.95	0.89	0.94	0.93	0.95
thymocyte	356	0.77	0.75	0.62	0.86	0.89	0.90	0.94	0.92
epithelial cell of proximal tubule	309	0.79	0.81	0.73	0.71	0.82	0.79	0.80	0.83
natural killer cell	321	0.83	0.82	0.74	0.80	0.74	0.76	0.80	0.83
naive B cell	357	0.45	0.23	0.34	0.32	0.36	0.51	0.54	0.47
hematopoietic stem cell	354	0.92	0.93	0.87	0.90	0.89	0.94	0.93	0.95
mature NK T cell	285	0.57	0.62	0.50	0.36	0.37	0.55	0.64	0.68
fibroblast	304	0.34	0.31	0.50	0.48	0.31	0.58	0.56	0.58
stromal cell	309	0.65	0.50	0.84	0.33	0.51	0.86	0.71	0.86
keratinocyte stem cell	329	0.93	0.94	0.88	0.93	0.89	0.95	0.88	0.96
erythroblast	300	0.65	0.73	0.71	0.71	0.63	0.68	0.73	0.80
Kupffer cell	296	0.97	0.95	0.65	0.84	0.90	0.97	0.97	0.98
megakaryocyte-erythroid progenitor cell	283	0.51	0.65	0.58	0.60	0.63	0.55	0.66	0.71
pancreatic acinar cell	251	0.98	0.98	0.94	1.00	1.00	0.99	0.99	0.99
luminal epithelial cell of mammary gland	264	0.92	0.91	0.95	0.92	0.89	0.93	0.93	0.95
professional antigen presenting cell	251	0.11	0.00	0.07	0.03	0.00	0.41	0.37	0.08
epidermal cell	214	0.88	0.87	0.82	0.88	0.82	0.87	0.85	0.90
hematopoietic precursor cell	207	0.60	0.76	0.41	0.39	0.39	0.67	0.75	0.78
oligodendrocyte	176	0.97	0.98	0.96	0.99	0.99	0.99	0.99	0.99
fibroblast of lung	170	0.95	0.94	0.95	0.89	0.93	0.96	0.94	0.95
CD8-positive, alpha-beta T cell	199	0.44	0.51	0.23	0.34	0.31	0.49	0.57	0.60
epithelial cell of large intestine	192	0.74	0.79	0.55	0.78	0.68	0.87	0.83	0.84
intestinal crypt stem cell	182	0.73	0.87	0.75	0.84	0.76	0.87	0.84	0.88
chondrocyte	169	0.76	0.63	0.78	0.74	0.68	0.77	0.80	0.78
immature T cell	184	0.63	0.00	0.15	0.71	0.85	0.84	0.88	0.83
precursor B cell	183	0.69	0.87	0.60	0.75	0.77	0.76	0.84	0.85
intermediate monocyte	182	0.45	0.06	0.41	0.27	0.49	0.45	0.51	0.57
large intestine goblet cell	173	0.79	0.87	0.83	0.82	0.79	0.91	0.88	0.90
CD4-positive, alpha-beta T cell	162	0.20	0.41	0.09	0.29	0.28	0.36	0.43	0.48
smooth muscle cell	164	0.64	0.77	0.71	0.68	0.73	0.84	0.80	0.78
leukocyte	180	0.46	0.55	0.31	0.44	0.36	0.63	0.64	0.72
plasma cell	155	0.53	0.63	0.50	0.58	0.46	0.55	0.62	0.70
lymphocyte	169	0.27	0.24	0.21	0.12	0.02	0.27	0.33	0.38
naive T cell	158	0.78	0.83	0.87	0.82	0.86	0.83	0.85	0.85
kidney loop of Henle thick ascending limb epithelial cell	157	0.91	0.92	0.68	0.73	0.78	0.91	0.90	0.93
immature B cell	149	0.65	0.72	0.61	0.78	0.66	0.53	0.65	0.83
alveolar macrophage	145	0.93	0.93	0.91	0.94	0.95	0.91	0.93	0.96
endothelial cell of hepatic sinusoid	141	0.95	0.97	0.88	0.91	0.95	0.99	0.96	0.98
fenestrated endothelial cell	144	0.80	0.92	0.68	0.57	0.79	0.87	0.84	0.93
lung macrophage	105	0.80	0.04	0.31	0.33	0.69	0.79	0.77	0.90
non-classical monocyte	110	0.62	0.68	0.48	0.60	0.62	0.77	0.71	0.73
endocardial cell	104	0.91	0.92	0.90	0.82	0.86	0.85	0.85	0.90
double negative thymocyte	102	0.59	0.00	0.35	0.49	0.72	0.70	0.72	0.78
kidney collecting duct principal cell	77	0.75	0.83	0.72	0.71	0.84	0.88	0.83	0.90
late pro-B cell	74	0.78	0.84	0.42	0.62	0.61	0.62	0.84	0.83
basal epithelial cell of tracheobronchial tree	84	0.80	0.85	0.88	0.72	0.74	0.91	0.81	0.94
mesenchymal cell	84	0.29	0.00	0.21	0.02	0.05	0.40	0.49	0.46
pancreatic A cell	75	0.62	0.73	0.71	0.75	0.85	0.88	0.89	0.82
adventitial cell	72	0.64	0.50	0.44	0.22	0.33	0.68	0.55	0.77
epithelial cell	73	0.45	0.07	0.65	0.46	0.30	0.54	0.59	0.63
kidney distal convoluted tubule epithelial cell	76	0.84	0.84	0.50	0.26	0.90	0.92	0.88	0.92
neutrophil	71	0.46	0.51	0.23	0.52	0.36	0.62	0.58	0.66
pancreatic ductal cell	41	0.99	0.94	0.88	0.96	0.95	0.92	0.93	0.98
myeloid dendritic cell	57	0.42	0.55	0.46	0.42	0.28	0.59	0.52	0.62
astrocyte	40	0.86	0.93	0.92	0.95	0.95	0.95	0.92	0.95
secretory cell	63	0.25	0.57	0.55	0.40	0.69	0.87	0.80	0.77
myeloid leukocyte	49	0.31	0.30	0.37	0.24	0.24	0.48	0.54	0.76
plasmatocyte	57	0.76	0.83	0.82	0.74	0.81	0.79	0.78	0.83
brain pericyte	35	0.45	0.75	0.55	0.75	0.67	0.88	0.89	0.84
neuron	46	0.46	0.57	0.73	0.73	0.77	0.80	0.80	0.83
vein endothelial cell	60	0.66	0.81	0.65	0.48	0.76	0.88	0.82	0.87
kidney collecting duct epithelial cell	25	0.32	0.50	0.12	0.42	0.58	0.58	0.66	0.84
pancreatic D cell	50	0.30	0.75	0.62	0.87	0.93	0.96	0.94	0.91
aortic endothelial cell	16	0.12	0.00	0.18	0.00	0.07	0.13	0.09	0.31
brush cell	35	0.85	0.64	0.29	0.87	0.78	0.78	0.81	0.91
erythroid progenitor cell, mammalian	47	0.67	0.00	0.43	0.19	0.28	0.52	0.62	0.82
regular atrial cardiac myocyte	24	0.29	0.42	0.30	0.29	0.28	0.41	0.55	0.68
kidney cortex artery cell	32	0.69	0.85	0.53	0.29	0.57	0.76	0.76	0.91
erythrocyte	26	0.62	0.60	0.65	0.76	0.79	0.66	0.75	0.91
mesangial cell	36	0.00	0.70	0.38	0.30	0.45	0.78	0.64	0.80
kidney loop of Henle ascending limb epithelial cell	30	0.00	0.53	0.34	0.18	0.48	0.60	0.60	0.62
cardiac muscle cell	40	0.79	0.85	0.66	0.93	0.22	0.99	0.96	1.00
mature alpha-beta T cell	34	0.00	0.16	0.00	0.33	0.38	0.26	0.46	0.31
basophil	32	0.68	0.66	0.62	0.57	0.40	0.59	0.64	0.73
cardiac valve cell	34	0.72	0.84	0.64	0.72	0.77	0.89	0.89	0.87
oligodendrocyte precursor cell	35	0.90	1.00	0.97	0.99	0.91	0.99	0.97	0.99
pulmonary alveolar type 2 cell	33	0.94	0.93	0.96	0.97	0.91	0.94	0.86	0.94
Schwann cell	21	0.75	0.78	0.86	0.76	0.79	0.69	0.78	0.79
pulmonary interstitial fibroblast	32	0.88	0.84	0.73	0.86	0.94	0.93	0.97	0.95
smooth muscle cell of trachea	24	0.00	0.08	0.15	0.21	0.20	0.58	0.48	0.15
granulocyte monocyte progenitor cell	29	0.00	0.61	0.74	0.59	0.63	0.89	0.75	0.87
interneuron	30	0.00	0.61	0.49	0.63	0.88	0.95	0.80	0.90
pancreatic PP cell	30	0.00	0.06	0.18	0.33	0.75	0.83	0.92	0.46
smooth muscle cell of the pulmonary artery	25	0.00	0.63	0.56	0.30	0.47	0.77	0.49	0.74
cell of skeletal muscle	23	0.94	0.89	0.84	0.93	0.85	0.94	0.92	0.96
brush cell of epithelium proper of large intestine	16	0.48	0.59	0.11	0.71	0.81	0.91	0.88	0.78
Langerhans cell	12	0.88	0.76	0.40	0.41	0.69	0.74	0.69	0.78
stem cell of epidermis	23	0.00	0.00	0.47	0.52	0.35	0.74	0.62	0.72
regulatory T cell	13	0.00	0.14	0.00	0.00	0.06	0.06	0.14	0.33
epithelial cell of thymus	20	0.00	0.00	0.33	0.33	0.13	0.40	0.28	0.29
enteroendocrine cell	16	0.00	0.70	0.38	0.81	0.86	0.91	0.80	0.88
kidney capillary endothelial cell	7	0.00	0.44	0.44	0.00	0.47	0.35	0.42	0.73
neuroepithelial stem cell	17	0.00	0.45	0.52	0.60	0.40	0.79	0.53	0.90
macrophage dendritic cell progenitor	18	0.00	0.34	0.58	0.10	0.65	0.44	0.42	0.67
DN3 thymocyte	12	0.00	0.00	0.00	0.73	0.59	0.49	0.59	0.73
regular ventricular cardiac myocyte	13	0.50	0.14	0.75	0.80	0.96	0.81	0.86	0.92
endothelial cell of lymphatic vessel	6	0.00	0.60	0.67	0.38	0.11	0.30	0.21	0.67
ciliated columnar cell of tracheobronchial tree	15	0.00	0.72	0.86	0.94	0.83	0.91	0.83	0.93
plasmacytoid dendritic cell	17	0.00	0.21	0.10	0.43	0.38	0.36	0.33	0.65
dendritic cell	10	0.00	0.47	0.40	0.43	0.20	0.56	0.53	0.69
medium spiny neuron	11	0.00	0.31	0.53	0.60	0.79	0.95	0.95	0.71
pericyte	7	0.74	0.88	0.88	1.00	0.93	0.88	0.82	0.93
neural stem cell	7	0.00	0.73	0.60	0.92	0.93	0.92	0.75	0.92
kidney proximal straight tubule epithelial cell	7	0.00	0.00	0.00	0.00	0.00	0.00	0.17	0.00
blood cell	7	0.16	0.00	0.00	0.00	0.00	0.09	0.17	0.00
immature NK T cell	10	0.00	0.00	0.00	0.00	0.40	0.30	0.31	0.00
cardiac neuron	6	0.00	0.44	0.50	0.25	0.50	0.46	0.53	0.50
mast cell	9	0.00	0.00	0.20	0.50	0.12	0.48	0.64	0.50
mucus secreting cell	6	0.00	0.34	0.67	0.77	0.55	0.80	1.00	1.00
early pro-B cell	6	0.00	0.50	0.00	0.25	0.56	0.40	0.50	0.67
pancreatic stellate cell	9	0.57	0.36	0.36	0.36	0.30	0.52	0.53	0.62
ependymal cell	4	0.75	0.86	0.86	1.00	0.67	0.86	0.86	0.86
Bergmann glial cell	7	0.00	0.60	0.60	0.92	0.88	0.92	0.73	0.83
neuroendocrine cell	3	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
fibrocyte	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
hepatic stellate cell	2	0.00	0.00	1.00	0.67	0.40	1.00	0.50	1.00
club cell	2	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
respiratory basal cell	8	0.00	0.00	0.00	0.67	0.52	0.93	0.93	0.67
kidney interstitial fibroblast	1	0.00	0.00	0.00	0.00	0.00	0.50	0.00	0.00
lymphoid lineage restricted progenitor cell	4	1.00	0.00	0.40	0.00	0.62	1.00	1.00	1.00
lung neuroendocrine cell	1	0.00	0.00	0.00	0.00	0.33	1.00	0.00	0.00
pulmonary alveolar type 1 cell	1	0.00	0.00	0.00	0.00	0.33	1.00	0.00	1.00
kidney cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
duct epithelial cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	scanvi	svm	xgboost	Consensus Prediction
B cell	32645	0.86	0.89	0.86	0.91	0.95	0.77	0.79	0.93
mesenchymal stem cell	14483	0.86	0.87	0.94	0.83	0.93	0.91	0.87	0.95
basal cell of epidermis	14129	0.85	0.87	0.89	0.91	0.81	0.87	0.83	0.91
granulocyte	13957	0.82	0.84	0.87	0.89	0.89	0.76	0.84	0.90
endothelial cell	13327	0.86	0.90	0.86	0.85	0.92	0.89	0.86	0.95
microglial cell	11930	0.99	0.99	0.92	0.99	0.98	0.99	0.99	0.99
T cell	11470	0.76	0.79	0.72	0.78	0.86	0.66	0.76	0.86
keratinocyte	11101	0.84	0.88	0.89	0.92	0.88	0.89	0.86	0.92
macrophage	8654	0.49	0.65	0.73	0.71	0.65	0.54	0.58	0.78
classical monocyte	7299	0.81	0.56	0.73	0.82	0.83	0.82	0.84	0.92
granulocytopoietic cell	7248	0.64	0.79	0.80	0.78	0.82	0.72	0.79	0.85
bladder urothelial cell	5993	0.99	0.98	0.97	0.97	0.97	0.99	0.98	0.99
mesenchymal stem cell of adipose tissue	5958	0.79	0.82	0.84	0.69	0.95	0.92	0.84	0.93
fibroblast of cardiac tissue	5682	0.94	0.93	0.84	0.70	0.96	0.96	0.91	0.97
endothelial cell of coronary artery	5423	0.81	0.84	0.77	0.73	0.94	0.90	0.86	0.95
skeletal muscle satellite cell	4307	0.98	0.97	0.96	0.98	0.97	0.97	0.96	0.98
proerythroblast	4228	0.56	0.52	0.64	0.69	0.77	0.57	0.69	0.71
kidney proximal convoluted tubule epithelial cell	4022	0.82	0.82	0.87	0.86	0.90	0.90	0.90	0.91
bronchial smooth muscle cell	4025	0.96	0.96	0.78	0.90	0.95	0.96	0.94	0.97
myeloid cell	3995	0.54	0.59	0.66	0.64	0.82	0.76	0.73	0.84
hepatocyte	3701	0.98	0.98	0.98	0.99	0.98	0.99	0.99	0.99
type B pancreatic cell	3606	0.97	0.97	0.95	0.98	0.98	0.99	0.98	0.99
bladder cell	3619	0.97	0.95	0.99	0.81	0.98	0.99	0.95	0.99
promonocyte	3427	0.60	0.70	0.79	0.81	0.89	0.81	0.83	0.87
DN4 thymocyte	3371	0.40	0.46	0.50	0.56	0.91	0.61	0.68	0.74
basal cell	3376	0.98	0.97	0.98	0.96	0.97	0.98	0.97	0.99
monocyte	3278	0.62	0.54	0.65	0.68	0.86	0.78	0.80	0.88
enterocyte of epithelium of large intestine	3294	0.91	0.92	0.93	0.94	0.92	0.95	0.94	0.95
thymocyte	3161	0.80	0.74	0.82	0.92	0.93	0.92	0.94	0.96
epithelial cell of proximal tubule	3126	0.80	0.77	0.84	0.82	0.87	0.86	0.86	0.87
natural killer cell	3038	0.83	0.81	0.69	0.82	0.83	0.80	0.84	0.87
naive B cell	3000	0.45	0.20	0.78	0.45	0.87	0.54	0.55	0.81
hematopoietic stem cell	2988	0.91	0.93	0.90	0.93	0.91	0.94	0.94	0.95
mature NK T cell	2876	0.59	0.63	0.54	0.74	0.85	0.64	0.72	0.77
fibroblast	2838	0.32	0.27	0.66	0.57	0.76	0.66	0.64	0.73
stromal cell	2814	0.66	0.39	0.94	0.52	0.92	0.87	0.74	0.93
keratinocyte stem cell	2728	0.92	0.92	0.91	0.93	0.92	0.94	0.89	0.96
erythroblast	2618	0.60	0.68	0.77	0.79	0.86	0.70	0.74	0.82
Kupffer cell	2508	0.96	0.94	0.85	0.93	0.95	0.98	0.97	0.98
megakaryocyte-erythroid progenitor cell	2509	0.53	0.63	0.69	0.66	0.73	0.64	0.72	0.77
pancreatic acinar cell	2466	0.98	0.95	0.92	0.99	0.98	0.99	0.99	0.99
luminal epithelial cell of mammary gland	2407	0.92	0.91	0.97	0.92	0.96	0.94	0.95	0.97
professional antigen presenting cell	2358	0.06	0.01	0.13	0.07	0.91	0.46	0.41	0.18
epidermal cell	2011	0.85	0.86	0.87	0.88	0.84	0.86	0.86	0.91
hematopoietic precursor cell	1937	0.62	0.71	0.53	0.67	0.92	0.73	0.81	0.87
oligodendrocyte	1918	0.98	0.99	0.95	0.99	0.99	1.00	0.99	0.99
fibroblast of lung	1836	0.96	0.95	0.91	0.91	0.98	0.98	0.96	0.98
CD8-positive, alpha-beta T cell	1741	0.45	0.50	0.27	0.52	0.66	0.59	0.66	0.70
epithelial cell of large intestine	1741	0.74	0.79	0.82	0.79	0.78	0.88	0.88	0.88
intestinal crypt stem cell	1736	0.74	0.85	0.87	0.86	0.85	0.90	0.89	0.91
chondrocyte	1736	0.73	0.63	0.83	0.81	0.87	0.87	0.88	0.87
immature T cell	1600	0.68	0.00	0.76	0.91	0.93	0.89	0.90	0.95
precursor B cell	1588	0.70	0.84	0.89	0.84	0.86	0.84	0.87	0.90
intermediate monocyte	1579	0.43	0.07	0.44	0.59	0.57	0.59	0.63	0.74
large intestine goblet cell	1572	0.82	0.84	0.90	0.84	0.91	0.94	0.92	0.94
CD4-positive, alpha-beta T cell	1559	0.22	0.35	0.27	0.38	0.66	0.50	0.56	0.64
smooth muscle cell	1540	0.64	0.76	0.80	0.80	0.89	0.88	0.85	0.83
leukocyte	1478	0.43	0.49	0.52	0.58	0.72	0.65	0.70	0.88
plasma cell	1491	0.53	0.63	0.75	0.73	0.81	0.63	0.69	0.79
lymphocyte	1432	0.26	0.23	0.59	0.27	0.81	0.34	0.46	0.64
naive T cell	1410	0.79	0.86	0.89	0.88	0.88	0.87	0.90	0.90
kidney loop of Henle thick ascending limb epithelial cell	1397	0.91	0.92	0.92	0.83	0.88	0.96	0.96	0.95
immature B cell	1266	0.68	0.70	0.73	0.78	0.82	0.67	0.72	0.89
alveolar macrophage	1221	0.94	0.94	0.91	0.93	0.93	0.95	0.95	0.98
endothelial cell of hepatic sinusoid	1149	0.94	0.95	0.84	0.93	0.95	0.97	0.96	0.98
fenestrated endothelial cell	1145	0.74	0.85	0.66	0.65	0.86	0.93	0.86	0.95
lung macrophage	1061	0.85	0.04	0.55	0.90	0.87	0.86	0.86	0.95
non-classical monocyte	1049	0.60	0.65	0.84	0.75	0.83	0.79	0.77	0.79
endocardial cell	949	0.92	0.92	0.92	0.87	0.91	0.92	0.90	0.95
double negative thymocyte	869	0.62	0.00	0.59	0.64	0.85	0.74	0.78	0.88
kidney collecting duct principal cell	866	0.77	0.91	0.91	0.86	0.92	0.96	0.95	0.97
late pro-B cell	869	0.76	0.79	0.82	0.77	0.81	0.75	0.88	0.94
basal epithelial cell of tracheobronchial tree	839	0.81	0.85	0.90	0.75	0.90	0.93	0.85	0.96
mesenchymal cell	795	0.29	0.00	0.26	0.15	0.46	0.51	0.58	0.54
pancreatic A cell	755	0.66	0.74	0.83	0.87	0.93	0.94	0.94	0.93
adventitial cell	742	0.69	0.56	0.81	0.33	0.87	0.83	0.65	0.89
epithelial cell	689	0.43	0.04	0.75	0.58	0.82	0.70	0.70	0.80
kidney distal convoluted tubule epithelial cell	668	0.81	0.89	0.90	0.69	0.93	0.96	0.95	0.94
neutrophil	634	0.50	0.50	0.63	0.72	0.72	0.67	0.65	0.79
pancreatic ductal cell	601	0.98	0.79	0.97	0.94	0.96	0.96	0.96	0.98
myeloid dendritic cell	561	0.47	0.53	0.79	0.50	0.64	0.72	0.62	0.77
astrocyte	552	0.89	0.93	0.96	0.96	0.96	0.99	0.99	0.99
secretory cell	500	0.28	0.34	0.76	0.49	0.85	0.92	0.88	0.89
myeloid leukocyte	467	0.45	0.38	0.77	0.37	0.77	0.62	0.67	0.94
plasmatocyte	439	0.73	0.81	0.88	0.79	0.92	0.90	0.90	0.94
brain pericyte	449	0.54	0.74	0.62	0.82	0.90	0.96	0.92	0.93
neuron	438	0.49	0.56	0.80	0.76	0.83	0.92	0.90	0.94
vein endothelial cell	412	0.60	0.78	0.75	0.64	0.85	0.87	0.80	0.90
kidney collecting duct epithelial cell	440	0.33	0.55	0.82	0.75	0.93	0.87	0.88	0.93
pancreatic D cell	412	0.28	0.69	0.85	0.91	0.94	0.97	0.96	0.96
aortic endothelial cell	420	0.09	0.01	0.07	0.26	0.64	0.41	0.34	0.76
brush cell	379	0.82	0.51	0.92	0.90	0.83	0.88	0.84	0.89
erythroid progenitor cell, mammalian	362	0.68	0.00	0.74	0.64	0.48	0.62	0.58	0.96
regular atrial cardiac myocyte	372	0.35	0.41	0.59	0.62	0.55	0.69	0.77	0.82
kidney cortex artery cell	349	0.74	0.84	0.69	0.55	0.85	0.88	0.86	0.95
erythrocyte	330	0.60	0.49	0.67	0.83	0.90	0.80	0.85	0.94
mesangial cell	314	0.00	0.67	0.53	0.64	0.82	0.86	0.81	0.93
kidney loop of Henle ascending limb epithelial cell	314	0.00	0.59	0.55	0.40	0.64	0.86	0.88	0.71
cardiac muscle cell	294	0.69	0.68	0.77	0.94	1.00	1.00	0.99	0.99
mature alpha-beta T cell	296	0.00	0.11	0.15	0.29	0.68	0.55	0.61	0.75
basophil	293	0.65	0.65	0.80	0.71	0.65	0.67	0.72	0.81
cardiac valve cell	281	0.71	0.82	0.71	0.84	0.88	0.92	0.93	0.91
oligodendrocyte precursor cell	277	0.91	0.97	0.96	0.97	0.90	1.00	0.99	1.00
pulmonary alveolar type 2 cell	259	0.94	0.94	0.95	0.94	0.95	0.97	0.94	0.96
Schwann cell	253	0.71	0.71	0.77	0.76	0.88	0.79	0.81	0.80
pulmonary interstitial fibroblast	239	0.88	0.86	0.87	0.88	0.89	0.91	0.94	0.97
smooth muscle cell of trachea	228	0.00	0.04	0.27	0.46	0.75	0.72	0.75	0.76
granulocyte monocyte progenitor cell	221	0.00	0.56	0.77	0.73	0.54	0.76	0.78	0.85
interneuron	210	0.00	0.53	0.69	0.70	0.89	0.97	0.94	0.95
pancreatic PP cell	198	0.00	0.09	0.63	0.71	0.88	0.92	0.92	0.90
smooth muscle cell of the pulmonary artery	184	0.00	0.75	0.76	0.46	0.59	0.83	0.67	0.86
cell of skeletal muscle	169	0.94	0.92	0.67	0.93	0.92	0.92	0.94	0.95
brush cell of epithelium proper of large intestine	159	0.55	0.72	0.77	0.78	0.84	0.97	0.95	0.90
Langerhans cell	163	0.92	0.81	0.86	0.72	0.72	0.78	0.83	0.97
stem cell of epidermis	148	0.00	0.00	0.60	0.75	0.16	0.61	0.64	0.84
regulatory T cell	157	0.00	0.02	0.00	0.01	0.26	0.41	0.40	0.75
epithelial cell of thymus	145	0.00	0.00	0.62	0.42	0.44	0.73	0.59	0.85
enteroendocrine cell	145	0.00	0.74	0.88	0.86	0.92	0.98	0.96	0.98
kidney capillary endothelial cell	154	0.00	0.37	0.32	0.33	0.78	0.90	0.89	0.94
neuroepithelial stem cell	134	0.00	0.07	0.81	0.50	0.55	0.85	0.66	0.93
macrophage dendritic cell progenitor	130	0.00	0.32	0.74	0.65	0.61	0.66	0.63	0.89
DN3 thymocyte	134	0.00	0.00	0.15	0.71	0.79	0.66	0.73	0.85
regular ventricular cardiac myocyte	131	0.46	0.03	0.80	0.75	0.94	0.94	0.98	0.99
endothelial cell of lymphatic vessel	134	0.00	0.47	0.94	0.57	0.32	0.66	0.54	0.91
ciliated columnar cell of tracheobronchial tree	112	0.00	0.82	0.92	0.88	0.91	0.91	0.97	0.99
plasmacytoid dendritic cell	105	0.00	0.28	0.80	0.32	0.40	0.58	0.51	0.78
dendritic cell	97	0.00	0.26	0.60	0.35	0.41	0.61	0.60	0.79
medium spiny neuron	92	0.00	0.00	0.92	0.75	0.79	1.00	0.97	0.98
pericyte	92	0.81	0.88	0.80	0.84	0.88	0.95	0.89	0.94
neural stem cell	90	0.00	0.61	0.75	0.86	0.86	0.96	0.98	0.97
kidney proximal straight tubule epithelial cell	88	0.00	0.00	0.00	0.00	0.43	0.64	0.43	0.35
blood cell	81	0.18	0.00	0.18	0.00	0.21	0.27	0.31	0.39
immature NK T cell	74	0.00	0.14	0.20	0.19	0.49	0.42	0.53	0.62
cardiac neuron	75	0.00	0.26	0.60	0.46	0.64	0.83	0.82	0.88
mast cell	67	0.00	0.00	0.55	0.65	0.69	0.72	0.65	0.94
mucus secreting cell	67	0.00	0.39	0.75	0.76	0.96	0.99	0.94	1.00
early pro-B cell	66	0.00	0.55	0.74	0.45	0.84	0.76	0.82	0.93
pancreatic stellate cell	60	0.84	0.67	0.90	0.60	0.54	0.72	0.86	0.93
ependymal cell	51	0.60	0.83	0.90	0.87	0.90	0.99	1.00	1.00
Bergmann glial cell	47	0.00	0.52	0.75	0.85	0.80	1.00	0.99	0.97
neuroendocrine cell	45	0.00	0.00	0.00	0.04	0.68	0.87	0.72	0.24
fibrocyte	41	0.00	0.00	0.00	0.30	0.37	0.43	0.63	0.68
hepatic stellate cell	37	0.00	0.36	0.24	0.68	0.76	0.90	0.88	0.97
club cell	35	0.00	0.43	0.50	0.57	0.70	0.80	0.80	0.70
respiratory basal cell	26	0.00	0.00	0.92	0.43	0.65	0.85	0.98	0.90
kidney interstitial fibroblast	15	0.00	0.00	0.97	0.63	0.32	0.62	0.77	0.97
lymphoid lineage restricted progenitor cell	9	0.94	0.00	0.80	0.20	0.32	0.95	0.95	0.94
lung neuroendocrine cell	7	0.00	0.00	0.73	0.22	0.52	0.93	0.93	0.93
pulmonary alveolar type 1 cell	3	0.00	0.00	0.00	0.00	0.33	1.00	1.00	1.00
kidney cell	3	0.00	0.00	0.00	0.00	0.10	0.19	1.00	0.50
duct epithelial cell	2	0.00	0.00	0.00	0.00	0.57	0.57	0.10	0.00

References

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse, The Tabula Muris Consortium, Nicole Almanzar, Jane Antony, Ankit S. Baghel, Isaac Bakerman, Ishita Bansal, Ben A. Barres, Philip A. Beachy, Daniela Berdnik, Biter Bilen, Douglas Brownfield, Corey Cain, Charles K. F. Chan, Michelle B. Chen, Michael F. Clarke, Stephanie D. Conley, Spyros Darmanis, Aaron Demers, Kubilay Demir, Antoine de Morree, Tessa Divita, Haley du Bois, Hamid Ebadi, F. Hernán Espinoza, Matt Fish, Qiang Gan, Benson M. George, Astrid Gillich, Rafael Gòmez-Sjöberg, Foad Green, Geraldine Genetiano, Xueying Gu, Gunsagar S. Gulati, Oliver Hahn, Michael Seamus Haney, Yan Hang, Lincoln Harris, Mu He, Shayan Hosseinzadeh, Albin Huang, Kerwyn Casey Huang, Tal Iram, Taichi Isobe, Feather Ives, Robert C. Jones, Kevin S. Kao, Jim Karkanias, Guruswamy Karnam, Andreas Keller, Aaron M. Kershner, Nathalie Khoury, Seung K. Kim, Bernhard M. Kiss, William Kong, Mark A. Krasnow, Maya E. Kumar, Christin S. Kuo, Jonathan Lam, Davis P. Lee, Song E. Lee, Benoit Lehallier, Olivia Leventhal, Guang Li, Qingyun Li, Ling Liu, Annie Lo, Wan-Jin Lu, Maria F. Lugo-Fagundo, Anoop Manjunath, Andrew P. May, Ashley Maynard, Aaron McGeever, Marina McKay, M. Windy McNerney, Bryan Merrill, Ross J. Metzger, Marco Mignardi, Dullei Min, Ahmad N. Nabhan, Norma F. Neff, Katharine M. Ng, Patricia K. Nguyen, Joseph Noh, Roel Nusse, Róbert Pálovics, Rasika Patkar, Weng Chuan Peng, Lolita Penland, Angela Oliveira Pisco, Katherine Pollard, Robert Puccinelli, Zhen Qi, Stephen R. Quake, Thomas A. Rando, Eric J. Rulifson, Nicholas Schaum, Joe M. Segal, Shaheen S. Sikandar, Rahul Sinha, Rene V. Sit, Justin Sonnenburg, Daniel Staehli, Krzysztof Szade, Michelle Tan, Weilun Tan, Cristina Tato, Krissie Tellez, Laughing Bear Torrez Dulgeroff, Kyle J. Travaglini, Carolina Tropini, Margaret Tsui, Lucas Waldburger, Bruce M. Wang, Linda J. van Weele, Kenneth Weinberg, Irving L. Weissman, Michael N. Wosczyna, Sean M. Wu, Tony Wyss-Coray, Jinyi Xiang, Soso Xue, Kevin A. Yamauchi, Andrew C. Yang, Lakshmi P. Yerra, Justin Youngyunpipatkul, Brian Yu, Fabio Zanini, Macy E. Zardeneta, Alexander Zee, Chunyu Zhao, Fan Zhang, Hui Zhang, Martin Jinye Zhang, Lu Zhou, James Zou; Nature, doi: https://doi.org/10.1038/s41586-020-2496-1

popV/tabula_muris_All

Model description

Metrics

References

popV/
tabula_muris_All