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Barangay – Name of the barangayDistrict – Manila district where the barangay is locatedNotes – Additional information about the barangay| Barangay | District | Notes |
|---|---|---|
| Baclaran | Tondo | Historic commercial area |
| Binondo | Binondo | Oldest Chinatown in the world |
| Sampaloc | Sampaloc | Known for universities and schools |
| Paco | Paco | Residential and commercial mix |
| Ermita | Ermita | Tourist and government center |
| Malate | Malate | Popular nightlife district |
| Santa Cruz | Santa Cruz | Commercial and residential |
| Pandacan | Pandacan | Known for oil depots and industry |
| Quiapo | Quiapo | Famous for Quiapo Church and market |
| San Miguel | San Miguel | Government offices located here |
| Tondo Central | Tondo | Densely populated |
| Port Area | Port Area | Manila South Harbor |
| Intramuros | Intramuros | Historic walled city |
| Sampaloc East | Sampaloc | Residential and school area |
| Santa Ana | Santa Ana | Oldest districts in Manila |
| San Nicolas | Binondo | Commercial area |