Transcription Run-On Grants Detection Of Regulatory elements (TROGDOR).
TROGDOR identifies transcription initiation regions (TIRs) from stranded nascent RNA sequencing data
(GRO-seq, PRO-seq, ChRO-seq, mNET-seq, etc.). It uses a 1D U-Net model and a tiled image segmentation
approach to achieve SOTA performance at predicting TIRs while maintaining computational efficiency.
The TROGDOR pipeline (including model module) can be installed using
pip install trogdor, or from
the source code at
https://github.com/adamyhe/trogdor