PPTStab: Prediction and Designing of thermostable proteins with a desired melting temperature

PPTStab is an ANN+MLP based ensemble regressor model developed to predict the melting temperature of long protein sequences and also design thermostable proteins. It integrates state-of-the-art LLMs like ProtBert, ProtT5-XL-UniRef50, Ankh, ProtGPT2, ProstT5 based embeddings into the architecture to advance the predictive modeling capabilities. It is designed for seamless usage, available via a webserver at https://webs.iiitd.edu.in/raghava/pptstab.

Please read/ cite the content about the PPTStab for complete information including working methodology and algorithm behind the approach.

If you use this method in your research, please cite:

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