from diffusers import AutoPipelineForText2Image
import torch

pipeline = AutoPipelineForText2Image.from_pretrained('ai-toolkit/Wan2.2-I2V-A14B-Diffusers-bf16', torch_dtype=torch.bfloat16).to('cuda')
pipeline.load_lora_weights('Mademon/I2V_Mal-lora', weight_name='I2V_Mal_low_noise.safetensors')
image = pipeline('a beautiful landscape').images[0]
image.save("my_image.png")

For more details, including weighting, merging and fusing LoRAs, check the documentation on loading LoRAs in diffusers