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SentenceTransformer(
(0): Transformer({'max_seq_length': 512, 'do_lower_case': False}) with Transformer model: XLMRobertaModel
(1): Pooling({'word_embedding_dimension': 1024, 'pooling_mode_cls_token': False, 'pooling_mode_mean_tokens': True, 'pooling_mode_max_tokens': False, 'pooling_mode_mean_sqrt_len_tokens': False, 'pooling_mode_weightedmean_tokens': False, 'pooling_mode_lasttoken': False, 'include_prompt': True})
(2): Normalize()
)pip install -U sentence-transformers1from sentence_transformers import SentenceTransformer
2
3# Download from the 🤗 Hub
4model = SentenceTransformer("FareedKhan/mixedbread-ai_deepset-mxbai-embed-de-large-v1_FareedKhan_prime_synthetic_data_2k_3_8")
5# Run inference
6sentences = [
7 '\nThe list you provided seems to be a mix of various chemical substances, some of which appear to be medications, others are chemical compounds, and a few could be substances from other fields (e.g., water treatment, food additives). To be more precise, it would be helpful to categorize them properly based on their common usage:\n\n### Medications and Drugs:\n- **Antibiotics**: Cefoxitin, Tobramycin, Amikacin\n- ** pain and inflammation relievers**: Benoxaprofen, Daptomycin, Ceftolozane, Salicylates (Benzydamine, Dexamethasone sodium phosphate)\n- **Intravenous fluids**: Magnesium trisilicate\n- **Antivirals**: Ribavirin, Inotersen\n- **Antibacterial agents**: Epirizole, Floctafenine, Flunixin\n- **Vaccines**: Vaborbactam, Brincidofovir, Adefovir\n- **Neuromodulators**: Cefatrizine, Bumadizone, Alminoprofen\n- **Cancer treatments**: Colistin, Nitrofurantoin, Sisomicin\n\n### Chemical Compounds:\n- **Salts and salts of acidity**: Fosfomycin, Azosemide, Mofebutazone\n- **Amino acids**: Phenylalanine, Nitrosalicylic',
8 'Which drugs interact with the SERPINA1 gene/protein as carriers?',
9 'Is there a regulatory function associated with the epidermal growth factor receptor or its interacting proteins in the control of genes or proteins that participate in the inactivation of fast sodium channels during Phase 1 of cardiac action potential propagation?',
10]
11embeddings = model.encode(sentences)
12print(embeddings.shape)
13# [3, 1024]
14
15# Get the similarity scores for the embeddings
16similarities = model.similarity(embeddings, embeddings)
17print(similarities.shape)
18# [3, 3]dim_768InformationRetrievalEvaluator| Metric | Value |
|---|---|
| cosine_accuracy@1 | 0.3911 |
| cosine_accuracy@3 | 0.4752 |
| cosine_accuracy@5 | 0.495 |
| cosine_accuracy@10 | 0.5545 |
| cosine_precision@1 | 0.3911 |
| cosine_precision@3 | 0.1584 |
| cosine_precision@5 | 0.099 |
| cosine_precision@10 | 0.0554 |
| cosine_recall@1 | 0.3911 |
| cosine_recall@3 | 0.4752 |
| cosine_recall@5 | 0.495 |
| cosine_recall@10 | 0.5545 |
| cosine_ndcg@10 | 0.467 |
| cosine_mrr@10 | 0.4398 |
| cosine_map@100 | 0.4462 |
positive and anchor| positive | anchor | |
|---|---|---|
| type | string | string |
| details |
|
|
| positive | anchor |
|---|---|
[object Object][object Object]Based on the provided information, it appears you are describing a complex biological system involving various molecules, drugs, diseases, and anatomical structures. Here's a breakdown:[object Object][object Object]### Key Entities[object Object]1. [object Object][object Object] - Mentioned molecules include metabolites, phenols, and drugs, with specific functional groups related to their chemical properties.[object Object] - Targets include enzymes (like acetyl-CoA carboxylase) and diseases causing various health conditions (e.g., Finnish type amyloidosis, lung cancer).[object Object][object Object]2. [object Object][object Object] - The molecules and drugs interact with various biological processes, pathways, and bodily systems.[object Object] | Identify common genetic targets that interact with both N-(3,5-dibromo-4-hydroxyphenyl)benzamide and 1-Naphthylamine-5-sulfonic acid. |
[object Object]The provided list appears to be a collection of gene symbols related to cancer. Gene symbols are used in genetics and molecular biology to identify genes. Each symbol is associated with a specific gene that plays a role in cellular functions, including cancer processes. When studying cancer, researchers often analyze these genes to understand their roles in tumor development, potential as targets for therapy, or as indicators for patient prognosis. For example, some genes listed are known oncogenes or tumor suppressor genes:[object Object][object Object]- TP53: A tumor suppressor gene that when mutated can lead to uncontrolled cell growth.[object Object]- P53, POLD1, PTEN: These are well-known tumor suppressors that help regulate cell division and DNA repair.[object Object]- BRCA | Which anatomical structures lack expression of genes or proteins involved in the homogentisate degradation pathway? |
[object Object][object Object]The gene in question appears to have a wide range of functions across various biological processes and body systems. It's involved in several key areas that regulate cellular responses, metabolic processes, and organ development. Here is a summary of its potential roles:[object Object][object Object]1. [object Object]: The gene contributes to growth control in cells, particularly in smooth muscle cells, and seems to influence cell proliferation, which is essential for tissue repair and development.[object Object][object Object]2. [object Object]: It plays a role in functions like signal transduction, neurotrophin signaling, and regulation of neural activity, suggesting it’s involved in neural health and development.[object Object][object Object]3. [object Object]: There is evidence linking | Identify genes or proteins that interact with angiotensin-converting enzyme 2 (ACE2) and are linked to a common phenotype or effect. |
MatryoshkaLoss with these parameters:
1{
2 "loss": "MultipleNegativesRankingLoss",
3 "matryoshka_dims": [
4 768
5 ],
6 "matryoshka_weights": [
7 1
8 ],
9 "n_dims_per_step": -1
10}eval_strategy: epochlearning_rate: 1e-05warmup_ratio: 0.1bf16: Truetf32: Falseload_best_model_at_end: Trueoverwrite_output_dir: Falsedo_predict: Falseeval_strategy: epochprediction_loss_only: Trueper_device_train_batch_size: 8per_device_eval_batch_size: 8per_gpu_train_batch_size: Noneper_gpu_eval_batch_size: Nonegradient_accumulation_steps: 1eval_accumulation_steps: Nonetorch_empty_cache_steps: Nonelearning_rate: 1e-05weight_decay: 0.0adam_beta1: 0.9adam_beta2: 0.999adam_epsilon: 1e-08max_grad_norm: 1.0num_train_epochs: 3max_steps: -1lr_scheduler_type: linearlr_scheduler_kwargs: {}warmup_ratio: 0.1warmup_steps: 0log_level: passivelog_level_replica: warninglog_on_each_node: Truelogging_nan_inf_filter: Truesave_safetensors: Truesave_on_each_node: Falsesave_only_model: Falserestore_callback_states_from_checkpoint: Falseno_cuda: Falseuse_cpu: Falseuse_mps_device: Falseseed: 42data_seed: Nonejit_mode_eval: Falseuse_ipex: Falsebf16: Truefp16: Falsefp16_opt_level: O1half_precision_backend: autobf16_full_eval: Falsefp16_full_eval: Falsetf32: Falselocal_rank: 0ddp_backend: Nonetpu_num_cores: Nonetpu_metrics_debug: Falsedebug: []dataloader_drop_last: Falsedataloader_num_workers: 0dataloader_prefetch_factor: Nonepast_index: -1disable_tqdm: Falseremove_unused_columns: Truelabel_names: Noneload_best_model_at_end: Trueignore_data_skip: Falsefsdp: []fsdp_min_num_params: 0fsdp_config: {'min_num_params': 0, 'xla': False, 'xla_fsdp_v2': False, 'xla_fsdp_grad_ckpt': False}fsdp_transformer_layer_cls_to_wrap: Noneaccelerator_config: {'split_batches': False, 'dispatch_batches': None, 'even_batches': True, 'use_seedable_sampler': True, 'non_blocking': False, 'gradient_accumulation_kwargs': None}deepspeed: Nonelabel_smoothing_factor: 0.0optim: adamw_torchoptim_args: Noneadafactor: Falsegroup_by_length: Falselength_column_name: lengthddp_find_unused_parameters: Noneddp_bucket_cap_mb: Noneddp_broadcast_buffers: Falsedataloader_pin_memory: Truedataloader_persistent_workers: Falseskip_memory_metrics: Trueuse_legacy_prediction_loop: Falsepush_to_hub: Falseresume_from_checkpoint: Nonehub_model_id: Nonehub_strategy: every_savehub_private_repo: Falsehub_always_push: Falsegradient_checkpointing: Falsegradient_checkpointing_kwargs: Noneinclude_inputs_for_metrics: Falseeval_do_concat_batches: Truefp16_backend: autopush_to_hub_model_id: Nonepush_to_hub_organization: Nonemp_parameters:auto_find_batch_size: Falsefull_determinism: Falsetorchdynamo: Noneray_scope: lastddp_timeout: 1800torch_compile: Falsetorch_compile_backend: Nonetorch_compile_mode: Nonedispatch_batches: Nonesplit_batches: Noneinclude_tokens_per_second: Falseinclude_num_input_tokens_seen: Falseneftune_noise_alpha: Noneoptim_target_modules: Nonebatch_eval_metrics: Falseeval_on_start: Falseuse_liger_kernel: Falseeval_use_gather_object: Falsebatch_sampler: batch_samplermulti_dataset_batch_sampler: proportional| Epoch | Step | Training Loss | dim_768_cosine_map@100 |
|---|---|---|---|
| 0 | 0 | - | 0.3930 |
| 0.0441 | 10 | 1.18 | - |
| 0.0881 | 20 | 1.0507 | - |
| 0.1322 | 30 | 0.9049 | - |
| 0.1762 | 40 | 0.8999 | - |
| 0.2203 | 50 | 0.6519 | - |
| 0.2643 | 60 | 0.5479 | - |
| 0.3084 | 70 | 0.6493 | - |
| 0.3524 | 80 | 0.4706 | - |
| 0.3965 | 90 | 0.5459 | - |
| 0.4405 | 100 | 0.5692 | - |
| 0.4846 | 110 | 0.7834 | - |
| 0.5286 | 120 | 0.5341 | - |
| 0.5727 | 130 | 0.5343 | - |
| 0.6167 | 140 | 0.4865 | - |
| 0.6608 | 150 | 0.3942 | - |
| 0.7048 | 160 | 0.3578 | - |
| 0.7489 | 170 | 0.5158 | - |
| 0.7930 | 180 | 0.3426 | - |
| 0.8370 | 190 | 0.5789 | - |
| 0.8811 | 200 | 0.5271 | - |
| 0.9251 | 210 | 0.577 | - |
| 0.9692 | 220 | 0.5193 | - |
| 1.0 | 227 | - | 0.4354 |
| 1.0132 | 230 | 0.4598 | - |
| 1.0573 | 240 | 0.2735 | - |
| 1.1013 | 250 | 0.2919 | - |
| 1.1454 | 260 | 0.3206 | - |
| 1.1894 | 270 | 0.2851 | - |
| 1.2335 | 280 | 0.3899 | - |
| 1.2775 | 290 | 0.3279 | - |
| 1.3216 | 300 | 0.2155 | - |
| 1.3656 | 310 | 0.3471 | - |
| 1.4097 | 320 | 0.327 | - |
| 1.4537 | 330 | 0.229 | - |
| 1.4978 | 340 | 0.2902 | - |
| 1.5419 | 350 | 0.3216 | - |
| 1.5859 | 360 | 0.2902 | - |
| 1.6300 | 370 | 0.4527 | - |
| 1.6740 | 380 | 0.1583 | - |
| 1.7181 | 390 | 0.3144 | - |
| 1.7621 | 400 | 0.2573 | - |
| 1.8062 | 410 | 0.2309 | - |
| 1.8502 | 420 | 0.3475 | - |
| 1.8943 | 430 | 0.3082 | - |
| 1.9383 | 440 | 0.3176 | - |
| 1.9824 | 450 | 0.2104 | - |
| 2.0 | 454 | - | 0.4453 |
| 2.0264 | 460 | 0.2615 | - |
| 2.0705 | 470 | 0.1599 | - |
| 2.1145 | 480 | 0.1015 | - |
| 2.1586 | 490 | 0.2154 | - |
| 2.2026 | 500 | 0.1161 | - |
| 2.2467 | 510 | 0.2208 | - |
| 2.2907 | 520 | 0.2035 | - |
| 2.3348 | 530 | 0.1622 | - |
| 2.3789 | 540 | 0.1758 | - |
| 2.4229 | 550 | 0.2782 | - |
| 2.4670 | 560 | 0.303 | - |
| 2.5110 | 570 | 0.1787 | - |
| 2.5551 | 580 | 0.2221 | - |
| 2.5991 | 590 | 0.1686 | - |
| 2.6432 | 600 | 0.2522 | - |
| 2.6872 | 610 | 0.1334 | - |
| 2.7313 | 620 | 0.1102 | - |
| 2.7753 | 630 | 0.2499 | - |
| 2.8194 | 640 | 0.2648 | - |
| 2.8634 | 650 | 0.1859 | - |
| 2.9075 | 660 | 0.2385 | - |
| 2.9515 | 670 | 0.2283 | - |
| 2.9956 | 680 | 0.1126 | - |
| 3.0 | 681 | - | 0.4462 |
1@inproceedings{reimers-2019-sentence-bert,
2 title = "Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks",
3 author = "Reimers, Nils and Gurevych, Iryna",
4 booktitle = "Proceedings of the 2019 Conference on Empirical Methods in Natural Language Processing",
5 month = "11",
6 year = "2019",
7 publisher = "Association for Computational Linguistics",
8 url = "https://arxiv.org/abs/1908.10084",
9}1@misc{kusupati2024matryoshka,
2 title={Matryoshka Representation Learning},
3 author={Aditya Kusupati and Gantavya Bhatt and Aniket Rege and Matthew Wallingford and Aditya Sinha and Vivek Ramanujan and William Howard-Snyder and Kaifeng Chen and Sham Kakade and Prateek Jain and Ali Farhadi},
4 year={2024},
5 eprint={2205.13147},
6 archivePrefix={arXiv},
7 primaryClass={cs.LG}
8}1@misc{henderson2017efficient,
2 title={Efficient Natural Language Response Suggestion for Smart Reply},
3 author={Matthew Henderson and Rami Al-Rfou and Brian Strope and Yun-hsuan Sung and Laszlo Lukacs and Ruiqi Guo and Sanjiv Kumar and Balint Miklos and Ray Kurzweil},
4 year={2017},
5 eprint={1705.00652},
6 archivePrefix={arXiv},
7 primaryClass={cs.CL}
8}